In vitro activity of LY146032 alone and in combination with other antibiotics against gram-positive bacteria.

نویسندگان

  • E Debbia
  • A Pesce
  • G C Schito
چکیده

The antibacterial activity of LY146032 alone and in combination with other drugs was assayed against gram-positive isolates. Synergism was found when LY146032 was combined with netilmicin, amikacin, imipenem, and fosfomycin by both checkerboard and time-kill tests. Indifference predominated when LY146032 was combined with teicoplanin, vancomycin, and rifampin. Under no circumstances and with no combinations was an antagonistic effect detected.

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عنوان ژورنال:
  • Antimicrobial agents and chemotherapy

دوره 32 2  شماره 

صفحات  -

تاریخ انتشار 1988